Tag: Genetics

Pharmacogenomics experts estimate that genetic factors account for 20 to 95 percent of patient variability in drug response. Understanding what are the 5 factors affecting drug metabolism is critical for optimizing medication therapy and preventing adverse reactions, as a drug's effectiveness can vary significantly from person to person.

Genetic factors alone can account for 20-95% of individual variability in response to some medications, highlighting the complexity of therapeutic outcomes. A patient's unique genetic makeup, coupled with other physiological conditions and concurrent drug interactions, determines what are three factors that can affect a medication action, ultimately impacting its efficacy and safety profile.

Approximately 90% of ingested alcohol is metabolized by the liver, with the remaining 10% eliminated through breath, urine, and sweat. Understanding what metabolises alcohol faster is crucial, as the rate is determined by a complex interplay of genetic and biological factors that cannot be rushed.

Affecting approximately 1 in every 57,000 people, late-onset Pompe disease is a rare genetic disorder caused by an enzyme deficiency. For many patients, the question, **'What is the drug Nexviazyme used for?'** is crucial. Nexviazyme is an enzyme replacement therapy specifically approved for treating late-onset Pompe disease in patients aged one year and older.

Over a decade ago, a large study in Spain was stopped early due to overwhelming evidence that the Mediterranean diet significantly reduced the risk of cardiovascular events, causing confusion for many who search "What is the medication Mediterranean used for?". In reality, the term does not refer to a pill but to a widely praised dietary pattern that can benefit long-term health.

Affecting roughly 1 in 185,000 newborns worldwide, Maple Syrup Urine Disease (MSUD) is a serious metabolic disorder that causes a distinctive sweet, syrupy odor. However, the most common reason for an adult wondering about a pill that makes you smell like syrup is often due to a dietary supplement, not a prescribed medication.

According to the American Cancer Society, about half of all melanomas have changes in the BRAF gene. A BRAF inhibitor is a targeted cancer drug that blocks the activity of the mutated BRAF protein, helping to stop cancer cells from growing and dividing uncontrollably.

The human genome encodes for five functional flavin-containing monooxygenase (FMO) enzymes, which play a significant role in the body's defense against potentially harmful foreign chemicals. These enzymes are primarily responsible for detoxifying and metabolizing a diverse range of drugs and xenobiotics, converting them into more water-soluble forms for excretion.

An estimated 80% to 90% of adults consume some form of caffeine every day, but how it affects you is largely dictated by a single, powerful liver enzyme. This crucial enzyme, known as CYP1A2, dictates your body's ability to process and eliminate caffeine, explaining why some people are unfazed by an espresso while others get the jitters from a single cup.

Over the past several decades, the definition of *pharming* has evolved to encompass two vastly different fields, with one being an advanced biotechnological process and the other a serious form of cybercrime. For those in the pharmacy profession, understanding **what is pharming in pharmacy** is crucial, as the term can refer to the production of pharmaceuticals using genetically modified organisms (GMOs) or a malicious online attack targeting sensitive data. This article will delve into both interpretations to provide a complete picture of the word's application in and around the pharmaceutical world.