Antidepressants Metabolized by CYP2C19 and the Role of Genetics
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4 min read
Up to 50% of undesirable drug reactions can be attributed to differences in how individuals metabolize medications. This variability is especially critical for antidepressants, where the cytochrome P450 (CYP) 2C19 enzyme plays a significant role in breaking down several commonly prescribed drugs. Understanding which antidepressants are metabolized by CYP2C19 is key to predicting efficacy, side effects, and optimizing treatment outcomes based on a person's unique genetic profile.
