Tag: Gi toxicity

According to the Arthritis Foundation, between 20% and 65% of rheumatoid arthritis (RA) patients taking methotrexate experience gastrointestinal problems, such as nausea and vomiting. This highlights that answering the question, **can methotrexate cause gastrointestinal toxicity?**, is critical for patients and healthcare providers alike.

Gastrointestinal disorders are among the most commonly reported adverse reactions to drugs, with some studies indicating they account for 40% of all adverse drug reactions [1.9.1]. Understanding what drugs cause GI toxicity is the first step in managing and mitigating these common side effects.