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Tag: Glycolysis

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Which enzymes catalyze irreversible reactions? A pharmacological perspective

4 min read
Did you know that a significant number of regulatory points in metabolic pathways are controlled by enzymes that catalyze reactions with large negative changes in Gibbs free energy, making them physiologically irreversible? Understanding which enzymes catalyze irreversible reactions is fundamental to both biochemistry and pharmacology, influencing everything from metabolic control to modern drug design.