Tag: Gpcrs

Drugs interact with specific receptors in the body, with approximately 30% of all approved drugs targeting G-protein-coupled receptors alone. A drug's effectiveness hinges on its ability to bind and modulate one of the four major types of drug receptors with examples for each, initiating a cascade of cellular events that lead to a therapeutic effect.

It is estimated that around 30% to 50% of all FDA-approved drugs target one of the four main types of drug receptors. Understanding what are the main types of drug receptors is fundamental to grasping how medications exert their therapeutic effects at a cellular level.