Does prednisone make a person grumpy? Understanding the Mood Side Effects
•
4 min read
According to a study cited by the NIH, severe psychiatric symptoms occurred in 1.3% of patients on lower-dose prednisone but increased significantly to 18.4% at higher doses, indicating that the medication definitely can cause mood changes, including irritability and grumpiness. This is because prednisone affects brain chemistry, influencing neurotransmitters that regulate mood.
