Can Diphenhydramine Make You Tired the Next Day? Understanding the 'Hangover Effect'
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4 min read
In a study of older adults using over-the-counter (OTC) sleep aids, 59% used a product containing diphenhydramine or doxylamine [1.4.5]. The primary question for many users is: **can diphenhydramine make you tired the next day?** The short answer is yes, due to a phenomenon often called the 'hangover effect' [1.2.1].