Tag: Hazardous drugs

According to the FDA, valproic acid is associated with multiple boxed warnings for life-threatening risks, including hepatotoxicity, teratogenicity, and pancreatitis. This makes it a hazardous drug requiring careful patient selection and monitoring.

Finasteride is classified as a hazardous drug, and a primary reason you have to wear gloves with finasteride is its ability to be absorbed through the skin [1.2.1, 1.4.3]. This poses significant risks, particularly to women who are pregnant or may become pregnant [1.6.5].

Approximately 1 in 500 patients on antiepileptic drugs like Topamax have reported suicidal thoughts or behaviors. This statistic highlights one of the many reasons why is Topamax considered hazardous, alongside other serious risks such as glaucoma and metabolic acidosis. The potential for severe adverse events requires a careful consideration of its use and risks.

Colchicine is an ancient anti-inflammatory drug with a narrow therapeutic index, meaning the difference between a therapeutic dose and a toxic dose is very small. This potent and potentially hazardous medication must be handled with extreme care, which is why you can't touch colchicine directly, especially in its powdered or uncontained forms.

The risk of fatal aplastic anemia in humans exposed to chloramphenicol is estimated to be approximately 1 in 25,000, underscoring the extreme caution required when handling this potent antibiotic. Therefore, it is critical to understand why you can't touch chloramphenicol or come into contact with it in any form.

In one study, the incidence of cardiac ischemic events like myocardial infarction and angina was 1.6% for patients on exemestane compared to 0.6% for those on tamoxifen [1.4.3, 1.4.5]. This highlights just one reason **why is exemestane hazardous** and requires careful medical supervision.