What is AT3 level in heparin? A Guide to Antithrombin and Heparin's Crucial Connection
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4 min read
Heparin's anticoagulant effect is dependent on a protein in the body, not a substance within the drug itself. This crucial cofactor is antithrombin III (AT3), and its level can significantly impact the success of heparin therapy. In fact, low AT3 levels are a primary cause of "heparin resistance," a condition where standard heparin doses fail to achieve therapeutic anticoagulation.
