Tag: Hepatic function

An estimated 4.5 million adults in the United States have been diagnosed with liver disease [1.11.1, 1.11.2]. The term 'hepatic' refers to the liver, so the question 'What is hepatic used for?' explores the pharmacology of medications that treat liver conditions [1.2.1, 1.2.2].

Approximately 90% of codeine and its metabolites are excreted from the body by the kidneys, but it is the liver that is the primary organ responsible for metabolizing the codeine into different compounds before it can be filtered for excretion. This dual-organ process is essential for the drug's journey through the body.