Tag: Hepatic impairment

As some of the oldest oral medications for type 2 diabetes, sulfonylureas have been used for over 60 years. However, they are associated with several key contraindications and precautions that must be considered before and during use, including the major risk of hypoglycemia.

In 2021, an estimated 21 million adults in the United States had at least one major depressive episode. For many, medications like desvenlafaxine are a key part of treatment, raising the important question: **is desvenlafaxine metabolized by the liver?**

Cisatracurium is predominantly cleared from the body through an organ-independent chemical process known as Hofmann elimination, a unique characteristic that differentiates it from many other neuromuscular blocking agents. This article explores how is cisatracurium cleared and the implications for its use in patients with compromised organ function.

According to the National Institutes of Health, while some liver enzyme elevations can occur during COVID-19 infection, clinical trials have shown no reported episodes of clinically apparent liver injury with short-term Paxlovid use. However, the key question remains: can you take Paxlovid if you have fatty liver disease? The answer depends on the severity of your liver condition.

Loperamide, the active ingredient in Imodium, has not been linked to clinically significant liver injury during standard use. This raises a common question: *Is Imodium hard on the liver*? In fact, the liver is crucial for its metabolism, especially in individuals with pre-existing liver conditions.