Tag: Hepatotoxicity

Diltiazem, a common calcium channel blocker, is associated with a low rate of mild and transient elevations in liver enzymes. While rare, cases of acute hepatic injury have been reported, so understanding the link between the medication and potential liver issues is important for patients asking: **Can diltiazem cause elevated liver enzymes?**.

Acetaminophen overdose is the leading cause of acute liver failure in the United States, accounting for over 50% of all reported cases. Understanding precisely **how many mg of acetaminophen is considered an overdose** is critical for preventing serious and potentially fatal liver damage.

Acetaminophen overdose is the leading cause of acute liver failure in the United States, according to the National Institutes of Health. This statistic highlights the critical importance of understanding what are the worst over the counter drugs for your liver, as even common medications can pose a serious risk when misused.

While nonsteroidal anti-inflammatory drugs (NSAIDs) are a frequent cause of drug-induced liver injury (DILI) in some studies, accounting for roughly 10% of cases, the actual risk of clinically apparent hepatotoxicity from their use remains very low. This begs the question: what NSAID is least harmful to the liver for the general population?

While historical anesthetic agents like halothane were linked to rare but severe liver damage, modern anesthetic agents are significantly safer for the liver. So, **is anesthesia hard on your liver** today? For the majority of healthy individuals, the risk of anesthetic-related liver injury is exceptionally low.

In March 2000, the first thiazolidinedione (TZD) approved for type 2 diabetes was voluntarily withdrawn from the market after being linked to at least 63 liver-failure deaths, causing many to ask: Which TZD was discontinued and why?.

Acetaminophen overdose accounts for approximately 56,000 emergency department visits, 2,600 hospitalizations, and 500 deaths in the United States annually. Understanding **what are the four stages of acetaminophen toxicity** is crucial for timely intervention.

According to the European Food Safety Authority (EFSA), the primary sources of furan exposure for children include milk-based products, fruit juices, and cereal-based products. This highlights the need to understand what furan does to the body and the potential health implications of this common food contaminant.

Over 1.5 million prescriptions for diphenhydramine, an active ingredient in some Unisom products, were written in 2020 alone, highlighting the widespread use of over-the-counter sleep aids. While the antihistamines in Unisom are generally safe for the liver when used correctly and for a short time, understanding the specific formula and risks, especially concerning liver health and potential acetaminophen content, is crucial.

According to a 2014 study in *Hepatology*, around 20% of liver toxicity cases in the United States are linked to herbal and dietary supplements, a number that has continued to rise. The notion that natural products are inherently safe has led many to question: **Can supplements cause liver damage**? The answer is a resounding yes, and understanding the reasons why is crucial for public health.