Tag: Herpes transmission

Clinical trials have shown that topical acyclovir can reduce the duration of viral shedding from lesions during initial genital herpes infections. However, the crucial question remains: **Does acyclovir cream reduce shedding** effectively enough to significantly impact transmission risk, especially during less visible, recurrent episodes? This requires a closer look at its mechanism and limitations.

Over 70% of genital herpes transmission occurs during periods of asymptomatic viral shedding. While antiviral medications cannot completely eliminate this phenomenon, they are highly effective at suppressing it. This article explores the pharmacology of how antivirals work to reduce the frequency and quantity of HSV shedding and the clinical implications for transmission and management.