Tag: Hismanal

In 1999, the antihistamine Astemizole, marketed as Hismanal, was globally withdrawn from the market following years of safety concerns over potentially fatal heart rhythm problems. This was a landmark event in pharmacovigilance, highlighting the significant danger posed by a medication that could disrupt the heart's electrical system.

The antihistamine astemizole, once sold under the brand name Hismanal, was voluntarily withdrawn from the market globally by its manufacturer Janssen in 1999 due to potentially fatal cardiovascular side effects. This means the answer to the question **Is astemizole still available?** is a definitive no, and for a very important reason rooted in patient safety.

In the late 1990s, concerns over severe cardiac side effects led the U.S. Food and Drug Administration (FDA) to request the removal of a popular medication, leaving many wondering **what antihistamine was pulled off the market?** The recalls of Seldane and Hismanal fundamentally reshaped the antihistamine landscape.