What Is the Most Serious Side Effect on the Use of Allopurinol?
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5 min read
Allopurinol hypersensitivity syndrome (AHS) is a severe adverse drug reaction that affects approximately 1 in 1000 patients prescribed allopurinol, carrying a reported mortality rate between 20% and 25%. To answer the question, what is the most serious side effect on the use of allopurinol? It is this rare yet devastating allergic reaction, and understanding its early signs and risk factors is crucial for minimizing its danger.