Tag: Hodgkin s lymphoma

First approved in the United States in 1969, the chemotherapy agent procarbazine has been a mainstay in treating certain types of cancer, especially when used in combination with other drugs,. The most commonly recognized brand name answering the question "What is another name for procarbazine?" is Matulane, although other versions exist globally. This drug belongs to a class of medications called alkylating agents, which work by targeting and damaging the DNA of cancer cells.

In a long-term study of patients with low-grade glioma, the addition of procarbazine-based chemotherapy to radiation therapy extended median overall survival from 7.8 years to 13.3 years [1.2.2]. This highlights the critical question: exactly how effective is procarbazine in modern oncology?

Dacarbazine, commonly known as **DTIC**, is a type of alkylating chemotherapy agent primarily used to treat certain cancers. It works by damaging the DNA of cancer cells, which prevents them from dividing and growing.

Approved for use in the United States in 1969, procarbazine remains a key chemotherapy drug used in combination regimens to treat advanced Hodgkin's lymphoma and certain brain cancers [1.7.3]. So, what does procarbazine do? It functions as an alkylating agent, slowing or stopping the growth of cancer cells [1.3.1].