Tag: Host factors

In the United States, over 2.8 million antimicrobial-resistant infections occur annually [1.10.1]. Given this, **what determines the choice of an antibiotic?** The decision is a complex process involving detailed evaluation of the host, the pathogen, and the drug itself to ensure effective treatment.

According to the CDC, over 2.8 million antibiotic-resistant infections occur annually in the U.S., highlighting the complexities of antimicrobial therapy. What does the effectiveness of antimicrobial treatment depend on involves a multifaceted interplay of pathogen, drug, and host factors that must be carefully managed.

Antimicrobial resistance was directly responsible for an estimated 1.27 million global deaths in 2019. The effectiveness of antimicrobials is a complex issue determined not by a single element, but by an intricate interplay of factors related to the pathogen, the drug itself, and the patient's biological environment.