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Tag: How long does benadryl last

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How Many Hours Does Benadryl Wear Off? Understanding Duration and Factors

4 min read
While the primary effects of a standard Benadryl dose, including drowsiness, typically last 4 to 6 hours, the active ingredient (diphenhydramine) remains in your system for a significantly longer period. This variation is key to understanding **how many hours does Benadryl wear off** for different individuals and why it's important to consider personal factors.