Tag: Hrt safety

While they sound alike, progesterone and progestin are distinct compounds with different safety profiles; for instance, research from the Women's Health Initiative (WHI) showed that synthetic progestins used with estrogen were linked to a higher incidence of breast cancer than estrogen alone. Understanding these differences is crucial when evaluating if **is progesterone safer than progestin**.

The use of menopausal Hormone Replacement Therapy (HRT) significantly declined after the 2002 Women's Health Initiative study raised initial safety concerns, but current understanding allows for greater personalization to minimize risks. Navigating these options to determine what is the safest hormone replacement therapy for an individual requires careful consideration with a healthcare provider.