Tag: Hus

A rare but life-threatening adverse event reported with valacyclovir is a blood disorder known as thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS), particularly in high-risk, immunocompromised patients. These serious conditions involve the formation of small blood clots that can damage organs.

While valacyclovir is not known to directly cause iron deficiency, a review of clinical data and case reports confirms it can be associated with rare and more serious forms of anemia. This is a crucial distinction for patients to understand, as the underlying mechanisms are different from simple iron malabsorption.