How does trazodone interact with hydrocodone? A critical overview
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4 min read
According to the National Institutes of Health, opioids like hydrocodone can carry a risk of serotonin syndrome when combined with other serotonergic agents. This makes it crucial to understand **how does trazodone interact with hydrocodone**, as this combination significantly increases the risk of both serotonin syndrome and severe central nervous system (CNS) depression.