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Tag: Hydrotropy

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Does Caffeine Bind to Sugar? Unpacking the Complex Molecular and Physiological Interactions

4 min read
According to molecular dynamics simulations and NMR experiments, sugars and caffeine *do* interact in beverages through a process of molecular stacking, which affects their distribution and solubility. This interaction fundamentally changes how they behave in solution, providing a much more complex answer to the question: **Does caffeine bind to sugar**?.