Tag: Hyperhomocysteinemia

According to MedlinePlus, around 25% of Hispanic people and 10 to 15% of North American whites have a common MTHFR gene variation. If you have an MTHFR variant and elevated homocysteine, understanding how to address this requires a targeted approach focusing on proper methylation support and dietary strategies. This guide explains how to lower your homocysteine levels with MTHFR, distinguishing between synthetic and active nutrients.

According to one recent study, excess synthetic folic acid intake in people with the MTHFR C677T variant can lead to the accumulation of unmetabolized folic acid (UMFA), which is associated with cognitive and psychiatric issues. This critical genetic variation highlights the fundamental difference between the body's processing of synthetic folic acid and natural folate, and why avoiding folic acid with MTHFR is a key consideration for many people.

Several studies have demonstrated that N-acetylcysteine (NAC) can significantly reduce homocysteine concentrations in the plasma, with some research showing reductions as high as 45% in certain populations. These findings have prompted a closer look at whether NAC can be a valuable tool in managing hyperhomocysteinemia, a condition associated with an increased risk of cardiovascular and neurodegenerative diseases.

According to scientific reviews, a significant number of commonly prescribed medications can increase homocysteine levels by interfering with the body's vitamin B metabolism. This guide provides insight into **what medications cause high homocysteine levels** and the underlying mechanisms.