The Rebound Effect and Risk Factors: Does Mannitol Increase Intracranial Pressure?
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5 min read
According to a Cochrane review of mannitol for acute traumatic brain injury, excessive or prolonged administration may cause mannitol to pass into the brain, where it might contribute to increased intracranial pressure. This finding offers a complex answer to the question: does mannitol increase intracranial pressure under specific, medically significant circumstances?