Tag: Icp

In a documented case involving a head-injured patient, the intravenous administration of metoclopramide was linked to a significant, acute increase in intracranial pressure (ICP). This rare but serious complication prompts a closer look at whether and how metoclopramide can increase intracranial pressure and its broader spectrum of neurological side effects.

Dexamethasone is the most commonly used corticosteroid for managing increased intracranial pressure (ICP) associated with brain tumors. This is because it potently reduces vasogenic edema and significantly lowers ICP. The question, however, is not simply, "**Does dexamethasone increase ICP?**" but rather, under which specific circumstances might its use be counterproductive or cause complications related to ICP?

According to a Cochrane review of mannitol for acute traumatic brain injury, excessive or prolonged administration may cause mannitol to pass into the brain, where it might contribute to increased intracranial pressure. This finding offers a complex answer to the question: does mannitol increase intracranial pressure under specific, medically significant circumstances?