Tag: Influenza a

Though once a frontline treatment, amantadine has not been recommended for influenza A treatment in the United States for many years due to widespread resistance. Its specific viral target reveals why its effectiveness was limited, answering the question: **What is the mechanism of action of amantadine in influenza?**.

Originally approved in 1966 as an antiviral medication for influenza A, the use of amantadine has evolved dramatically, with its primary applications now centered on neurological conditions like Parkinson's disease. However, it is no longer effective or recommended for treating the flu due to widespread viral resistance.