Tag: Insulin secretagogues

According to the American Diabetes Association, meglitinides are one class of oral medications prescribed to help manage blood sugar levels in adults with type 2 diabetes. This rapid-acting group of drugs includes specific agents like nateglinide and repaglinide, which work by stimulating the pancreas to release insulin in response to a meal.

Although their use has declined, sulfonylureas have been a mainstay in treating Type 2 Diabetes (T2D) for over 60 years and can decrease glycated hemoglobin A1C (HbA1c) by 1% to 1.25%. So, what are sulfonylureas and how do they work?