Tag: Intrathecal

Polymyxin B is a potent, older-class antibiotic used primarily as a last-resort treatment for serious infections caused by multi-drug resistant gram-negative bacteria, such as *Pseudomonas aeruginosa*. This medication is not given orally due to poor absorption and must be administered through specialized routes depending on the infection's location and severity.

Tofersen, an antisense oligonucleotide marketed as Qalsody, was approved by the FDA for the treatment of SOD1-ALS, a rare and devastating form of amyotrophic lateral sclerosis. Like all potent medications, it is associated with a range of potential side effects, from common discomforts to serious neurological complications.