What is the difference between intrinsic and idiosyncratic hepatotoxicity?
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4 min read
According to a U.S. Pharmacist report, drug-induced liver injury (DILI) affects an estimated 10 to 15 per 100,000 people, making it a significant health concern. Understanding **what is the difference between intrinsic and idiosyncratic hepatotoxicity** is crucial for both clinicians and patients, as these represent two distinct pathways by which medications can cause liver damage. One is a predictable, dose-dependent reaction, while the other is a rare and unpredictable event driven by host-specific factors.
