Tag: Ion channels

Epilepsy affects approximately 50 million people worldwide, making it one of the most common neurological diseases globally [1.3.3]. The primary treatment involves medications that stabilize the brain's electrical activity. So, what is the mechanism of action of antiepileptic drugs (AEDs)?

Approximately one-third of people with epilepsy have drug-resistant seizures, highlighting the importance of understanding the intricate **mechanism of action of clinically approved anti seizure drugs**. These medications work in various ways to restore the crucial balance between excitatory and inhibitory signaling in the brain to prevent seizures.

Over 65 million people worldwide live with epilepsy, a chronic neurological disorder characterized by recurrent seizures. To control these seizures, anti-seizure drugs work by addressing the core mechanisms of neuronal hyperexcitability and hypersynchrony. What mechanism of action do anti seizure drugs work through? By modulating key processes in the brain's electrical circuitry, including neurotransmitter balance and ion channel function.

Recent analysis shows that over 95% of known drug targets are proteins [1.3.1]. These proteins facilitate how medications work, but what are the four main targets for drug action that are most crucial for therapeutic effects? [1.2.1, 1.2.4]

Nearly 50% of people in the United States have used at least one prescription drug in the last 30 days [1.8.1]. Understanding **what are the 4 main drug actions** is key to grasping how these medications work in the body to produce their therapeutic effects.