Tag: Irreversible damage

While Zolgensma has been a life-altering gene therapy for infants with Spinal Muscular Atrophy (SMA), experts widely agree that **Why is Zolgensma not a cure?** is a critical question for managing patient expectations. The single-dose treatment halts disease progression but cannot reverse pre-existing neurological damage, a key distinction from a complete cure.

Vancomycin is a critical antibiotic used in up to 35% of hospitalized patients for serious gram-positive infections, but it carries significant risks [1.2.1]. Understanding what are the irreversible damage caused by vancomycin is crucial for patient safety.

According to the American Academy of Family Physicians, while aminoglycoside nephrotoxicity is typically reversible, ototoxicity from these same antibiotics is usually irreversible. This significant difference in outcome is crucial for patients and clinicians considering the use of these potent antibiotics. Understanding the underlying mechanisms is key to managing the risks associated with aminoglycoside toxicity.

According to one study, up to 50% of patients on oral corticosteroids will develop bone fractures over the long term, highlighting the serious risks involved. Understanding what are the permanent side effects of steroids is crucial for both medically treated patients and those misusing anabolic substances.

For many patients, corticosteroids like prednisone are life-saving, but they come with a range of potential side effects, many of which can resolve after treatment stops. Whether *is prednisone damage reversible* depends largely on the duration and dosage of the therapy and the specific side effect in question.