Is levofloxacin an enzyme inhibitor? Understanding Its Mechanisms
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4 min read
Levofloxacin's primary mechanism of action involves inhibiting essential bacterial enzymes, DNA gyrase and topoisomerase IV, to kill bacteria. When considering its effect on human drug-metabolizing enzymes, particularly the cytochrome P450 (CYP) system in the liver, the answer to 'is levofloxacin an enzyme inhibitor?' is more nuanced and involves a different set of targets.