Tag: Kratom alkaloids

According to recent studies, the alkaloids found in kratom, particularly mitragynine and its metabolites, do interact with serotonin receptors in the brain. This complex interaction is one of the multiple mechanisms of action that contributes to kratom’s diverse psychoactive effects, including mood enhancement and anxiety reduction reported by some users.

Mitragynine (MIT), the most abundant active alkaloid in kratom, can comprise anywhere from 1-6% of the dry leaf weight, but this percentage varies significantly. This wide variability is crucial for understanding how much kratom is in MIT, a term that refers not only to the alkaloid itself but often to commercial products designed for high potency.

While kratom contains alkaloids that act on opioid receptors, structurally they are distinct from classic opiates like morphine or heroin. As a result, kratom does not show up as an opiate on standard drug tests. However, depending on the test type, and factors like dosage and individual metabolism, detection is possible.