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Tag: Last

Explore our medication guides and pharmacology articles within this category.

What are the symptoms of anesthesia overdose?

3 min read
While anesthesia-related mortality is low, with estimates around 1 in 100,000 to 200,000 cases, a significant portion of these incidents are linked to overdose. Recognizing what are the symptoms of anesthesia overdose is critical for patient safety and immediate intervention.

Which is a disadvantage of local anesthesia? Understanding the Risks and Limitations

4 min read
While local anesthesia is generally considered safe and effective for minor procedures, with major events like seizures occurring in less than 3% of cases, it is not without its potential drawbacks. Understanding these limitations and risks is crucial for both healthcare providers and patients considering this option. One of the most significant, though rare, disadvantages of local anesthesia is Local Anesthetic Systemic Toxicity (LAST).

What happens when lidocaine gets in the bloodstream?

4 min read
The incidence of severe Local Anesthetic Systemic Toxicity (LAST) is estimated to be between 1 and 2 per 1,000 nerve blocks. Knowing what happens when lidocaine gets in the bloodstream is critical for patient safety during procedures using local anesthetics.

Understanding When Should Intralipid Infusion Be Done?

5 min read
Intralipid, a sterile fat emulsion, has been a key component in clinical medicine for decades, notably gaining attention for its use in treating local anesthetic systemic toxicity. Knowing when should Intralipid infusion be done is critical, as its application and timing vary dramatically depending on the patient’s clinical need, ranging from emergency situations to long-term nutritional support.

What Happens if Lidocaine Gets Into Your Bloodstream?

5 min read
Inadvertent intravascular injection is a primary cause of local anesthetic systemic toxicity (LAST). The effects of this can range from mild neurological symptoms to severe cardiovascular collapse. Understanding **what happens if lidocaine gets into your bloodstream** is critical for recognizing the signs and acting quickly in an emergency.

How quickly does lidocaine toxicity happen? A timeline and risk factors

4 min read
Approximately 75% of local anesthetic systemic toxicity (LAST) cases manifest within the first five minutes of administration, particularly following an intravascular injection. The speed of onset depends heavily on the route of administration, making the question of how quickly does lidocaine toxicity happen a critical consideration in clinical practice.

How Do You Treat LAST Toxicity?: A Guide to Local Anesthetic Systemic Toxicity Management

4 min read
Although rare, local anesthetic systemic toxicity (LAST) can be a life-threatening complication, with an estimated incidence ranging from 7.5 to 20 per 10,000 peripheral nerve blocks. Knowing how to treat LAST toxicity with a rapid and coordinated response is critical for patient survival, centering on immediate intervention and specific resuscitation protocols.

What are signs of lidocaine toxicity?

5 min read
Local anesthetic systemic toxicity (LAST) is a rare but life-threatening complication that can arise from excessive plasma concentrations of local anesthetic medications like lidocaine. Understanding **what are signs of lidocaine toxicity?** is crucial for patients and medical professionals alike, as early recognition is key to preventing severe and potentially fatal outcomes. This condition can affect both the central nervous system (CNS) and the cardiovascular system, with symptoms that can escalate rapidly.