Tag: Lean body weight

According to guidelines from the Pediatric Pharmacy Association, the transition from pediatric to adult dosing can occur in patients weighing 40 kg or more. However, the answer to **what weight is considered adult dosing?** is more complex, involving a patient's unique physiology and the specific drug's properties.

Pharmacokinetic studies have shown that lean body weight (LBW) can be a critical metric for guiding medication dosing, particularly in cases where body composition significantly impacts drug distribution and clearance. Knowing when to use lean body weight is essential to achieve therapeutic effectiveness and minimize adverse effects, as using alternative weight metrics can lead to over- or underdosing depending on the drug's properties.