Tag: Lenmeldy

With a list price of $4.25 million per dose, Lenmeldy became the most expensive prescription drug on the market after its FDA approval in early 2024. This staggering figure highlights how recent breakthroughs in gene therapy are redefining what is the most expensive prescription drug and sparking critical discussions about access and cost.

As of late 2024 and into 2025, the one-time gene therapy Lenmeldy (atidarsagene autotemcel) for metachromatic leukodystrophy holds the title of the most expensive infusion drug, with a staggering list price of $4.25 million. This represents a new peak in the rapidly evolving landscape of ultra-high-cost pharmaceuticals, dominated by groundbreaking gene therapies for rare genetic diseases.

Priced at $4.25 million for a single infusion, Kyowa Kirin's Lenmeldy is currently the most expensive drug substance in the world. This one-time gene therapy is a groundbreaking treatment for the ultra-rare genetic disorder metachromatic leukodystrophy (MLD), highlighting the high costs associated with advanced therapeutic innovation.

With a price tag of $4.25 million for a single treatment, Lenmeldy, a gene therapy for metachromatic leukodystrophy (MLD), is the highest-priced drug in the U.S.. This staggering figure brings critical attention to the complex market of specialized medicines, forcing us to ask: which drug has the highest price and why?.

As of 2025, the most expensive medication in the U.S. is Lenmeldy, a gene therapy priced at $4.25 million per dose [1.2.7]. This article answers **what is the most expensive medication in the US?** and explores the groundbreaking science and complex economics behind these costly treatments.

With a price tag of **$4.25 million** for a one-time dose, Lenmeldy is currently the most expensive prescription drug in the world [1.2.2, 1.4.1, 1.4.3]. This article explores what the most expensive prescription drug in the world is and the factors driving its multimillion-dollar cost.

As of March 2024, the world's most expensive drug is Lenmeldy, a one-time gene therapy injection priced at $4.25 million [1.6.8, 1.2.4]. This article answers: **What is the richest injection in the world?**, exploring the medications commanding multi-million dollar price tags.

With a price tag of $4.25 million per one-time treatment, Lenmeldy, a gene therapy for a rare genetic disorder, holds the record for **what is the most expensive drug ever sold**. This staggering cost for a single dose highlights the unprecedented pricing of modern gene therapies and raises important questions about healthcare affordability and access.

With a price tag of **$4.25 million**, Lenmeldy holds the title for the world's most expensive medical injection [1.4.2]. This one-time gene therapy treats metachromatic leukodystrophy (MLD), a rare, fatal genetic disorder affecting about one in 40,000 Americans [1.4.2, 1.7.6].