Tag: Leucovorin

Between 7% and 30% of patients stop methotrexate therapy within the first year due to toxicity [1.2.3]. So, **what vitamin can reduce the toxicity of methotrexate?** The answer lies in forms of vitamin B9: folic acid and folinic acid.

Chemotherapy side effects can be severe, prompting the use of supportive medications that modify the effects of the primary drug. Leucovorin is a prime example of such an agent, as its precise application and purpose depend on the specific chemotherapy drug it's combined with. A critical question for patients and healthcare providers alike is: Which purpose does leucovorin serve as part of a chemotherapy protocol, and why does its function change depending on the regimen?

Autism Spectrum Disorder (ASD) affects approximately 2% of children in the United States [1.3.7]. Amidst ongoing research for effective therapies, a key question has emerged: Is leucovorin a surprising autism treatment for a specific subset of these children? [1.3.7, 1.7.4]

Leucovorin, a medication also known as folinic acid, is a crucial component in certain cancer treatments and can act as an antidote to the side effects of specific chemotherapies. A primary purpose of leucovorin is to protect healthy cells from harm during high-dose chemotherapy regimens.