Tag: Leukotrienes

Overproduction of inflammatory mediators from the 5-lipoxygenase (5-LOX) pathway is a major cause of conditions like asthma and allergic rhinitis. The question of **what is lox in inflammation** is complex, as 'LOX' is an acronym for several different enzyme and receptor families that play varied roles in inflammatory processes.

Asthma symptoms, such as wheezing and coughing, are often more severe during the nighttime and early morning due to natural circadian rhythms. This physiological reality is the primary reason why is it important to take montelukast at night for patients with asthma, as it strategically aligns the medication's peak effect with the period of greatest need.

Leukotrienes are potent pro-inflammatory lipid mediators, and their overproduction is linked to significant pathological features of asthma and allergies. But **what is the function of the leukotrienes** in both normal physiological processes and in disease states?