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Tag: Lifespan

Explore our medication guides and pharmacology articles within this category.

Do Antidepressants Affect Lifespan? Sorting Fact from Fiction on Long-Term Use

4 min read
According to a 2025 analysis published in *PLOS ONE*, overall antidepressant use in individuals with depression showed no statistically significant association with all-cause mortality after controlling for confounding factors, though initial unadjusted rates appeared higher. However, the question "Do antidepressants affect lifespan?" remains complex, with conflicting studies and a critical need to differentiate between the effects of medication and the profound impact of the underlying illness itself.