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Tag: Locus coeruleus

Explore our medication guides and pharmacology articles within this category.

Do Benzodiazepines Increase Norepinephrine? Understanding the Neurochemical Impact

4 min read
Benzodiazepines enhance the calming effects of the neurotransmitter GABA, a mechanism that causes a widespread suppression of neural activity. This leads many to ask, **do benzodiazepines increase norepinephrine**, as the medication's overall effect is one of sedation and reduced anxiety, which directly opposes the action of norepinephrine. The answer is complex, but in most cases, these drugs cause a decrease in norepinephrine levels during acute use, with a rebound increase during withdrawal.