Does Doxycycline Penetrate the CNS? A Pharmacological Review
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4 min read
Studies show doxycycline achieves a mean penetration into cerebrospinal fluid (CSF) of approximately 14% to 26% of serum levels [1.2.1, 1.2.2]. This article examines the critical question: **Does doxycycline penetrate the CNS** effectively enough for clinical use?