Does metformin cause lactic acidosis? Understanding the Real Risk
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4 min read
The incidence of metformin-associated lactic acidosis (MALA) is rare, estimated to be between 2 and 9 cases per 100,000 patient-years [1.2.2, 1.2.5]. While the question 'Does metformin cause lactic acidosis?' is common, the reality is the risk is very low for most patients [1.2.1].