Tag: Mecasermin

Over 99% of Insulin-like Growth Factor 1 (IGF-1) in the bloodstream is bound to carrier proteins, which significantly regulates its bioavailability [1.5.1]. The critical question for alternative administration is: can IGF-1 be absorbed sublingually to bypass traditional injections and digestive breakdown?

Synthetic IGF-1 is a regulated pharmaceutical drug and is not legally available as a dietary supplement. The direct and definitive answer to the question, "Do I need a prescription for IGF-1?", is yes, for all legitimate pharmaceutical-grade products.

In clinical trials, hypoglycemia (low blood sugar) was the most common adverse reaction to mecasermin, the lab-created form of IGF-1, affecting 47% of patients [1.8.2]. Understanding what are the side effects of IGF-1 growth hormone is critical for anyone considering or undergoing this therapy.