Tag: Mechanism

Tianeptine was originally characterized as a selective serotonin reuptake enhancer, but recent research has revealed a far more complex and atypical mode of action, including potent activity at opioid receptors. This multifaceted pharmacology distinguishes it from traditional antidepressants and explains its diverse effects on mood and pain.

Aminoglycoside antibiotics cause irreversible hearing loss and balance problems in up to 10% of patients receiving these drugs intravenously. The intricate mechanism of aminoglycoside ototoxicity involves a cascade of damaging intracellular events that lead to the permanent destruction of sensory hair cells in the inner ear.