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Tag: Mediators

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Why Do Antihistamines Not Work for Anaphylaxis?

7 min read
Every year, thousands of people mistake antihistamines for a suitable treatment for severe allergic reactions, a dangerous misconception that can have fatal consequences. A severe, systemic allergic reaction, known as anaphylaxis, requires immediate and specific treatment that an antihistamine simply cannot provide. The fundamental reason why antihistamines do not work for anaphylaxis lies in the complex cascade of chemical mediators released throughout the body, most of which are unaffected by antihistamine medications.