What is the major side effect of lidocaine? Understanding Local Anesthetic Systemic Toxicity
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4 min read
Systemic toxicity is the most significant adverse effect of lidocaine, a common local anesthetic, and it can affect the central nervous system and heart. While many side effects are mild and localized, severe complications can occur if the medication is absorbed into the bloodstream in large amounts, particularly from injections or overuse of topical forms.