Tag: Mesalamine

Over the past decade, several branded mesalamine products like Asacol and Asacol HD have been voluntarily discontinued by their manufacturers for commercial and regulatory reasons. While this is a significant development, it does not mean the entire medication class is being discontinued, but rather reflects strategic business decisions, leaving many patients wondering why is mesalamine being discontinued.

According to a Cochrane review, there is no significant difference in the overall efficacy of sulfasalazine and mesalamine for the treatment of ulcerative colitis. However, determining which is better, sulfasalazine or mesalamine, involves a deeper look into their side effect profiles, specific indications, and available formulations.

Nearly 3 million adults in the United States have been diagnosed with Inflammatory Bowel Disease (IBD), and finding an effective treatment strategy is crucial. For those managing conditions like Ulcerative Colitis or Crohn's Disease, figuring out which medications can be combined safely is a common question. For example, 'Can you take mesalamine and budesonide together?', is a question with a clear answer: under a doctor's supervision, yes, as these two medications can be used in combination to manage flare-ups and maintain remission.

According to clinical trials, a skin rash was reported in 6% of adults and 5% of children using mesalamine. This means that while mesalamine is generally safe for managing inflammatory bowel disease, experiencing a skin rash is a recognized, albeit relatively common, potential side effect that requires attention.

According to drug interaction databases, combining mesalamine with other medications that can affect the kidneys, such as meloxicam, may increase the risk of kidney damage. Due to this significant risk, anyone asking, 'Can you take meloxicam with mesalamine?', must consult a healthcare professional before combining these two drugs.

According to the British National Formulary, taking cephalexin and mesalamine (also known as mesalazine) together can increase the risk of nephrotoxicity (kidney damage) [1.2.5]. If you are prescribed both, it is essential to understand the potential risks.

While mesalamine is a primary treatment for reducing inflammation in inflammatory bowel disease (IBD), leading to a reduction in diarrheal symptoms, studies show it can paradoxically cause diarrhea as a potential side effect. Understanding whether this is a minor issue or a sign of drug intolerance is crucial for proper management.

Pentasa is prescribed to approximately 1.5 million people in the US for inflammatory bowel diseases (IBD) [1.7.1]. For many patients, a key question is: **Do Pentasa side effects go away?** This article explores the duration and management of these effects.

Did you know that taking certain common medications, such as ibuprofen, can significantly increase your risk of kidney damage when combined with Pentasa? Understanding what not to take with Pentasa is critical for patients with inflammatory bowel disease to avoid potentially serious adverse effects from drug interactions.

Approximately 50% of patients with mild-to-moderate inflammatory bowel disease (IBD) will fail first-line mesalamine therapy, necessitating a conversation with their healthcare provider about what is the next step after mesalamine. This progression involves moving to more potent medications or adding adjunctive therapies, depending on disease severity and type.