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Tag: Methemoglobinemia

Explore our medication guides and pharmacology articles within this category.

What is the major side effect of lidocaine? Understanding Local Anesthetic Systemic Toxicity

4 min read
Systemic toxicity is the most significant adverse effect of lidocaine, a common local anesthetic, and it can affect the central nervous system and heart. While many side effects are mild and localized, severe complications can occur if the medication is absorbed into the bloodstream in large amounts, particularly from injections or overuse of topical forms.

What is stronger, benzocaine or lidocaine? A pharmacological comparison

3 min read
While both are local anesthetics used for pain relief, a study showed that a 20% benzocaine solution was as effective as a 5% lidocaine solution for numbing prior to a needle insertion. This example highlights that potency isn't just about concentration but a complex interplay of chemical properties, leading to the crucial question: what is stronger, benzocaine or lidocaine?.

What is an Absolute Contraindication of Using a Local Anesthetic?

5 min read
While local anesthetics are extremely common and generally safe, a known, documented allergy to a specific agent is the most clear-cut absolute contraindication of using a local anesthetic, as any administration could trigger a life-threatening anaphylactic reaction. Clinicians must distinguish between true allergic responses and other adverse events when evaluating patient history.

Why is numbing cream not recommended? Unveiling the Hidden Dangers

5 min read
The Food and Drug Administration (FDA) has issued repeated warnings regarding the use of certain over-the-counter numbing creams, citing serious and potentially life-threatening side effects. A common misconception is that topical numbing agents are harmless, but improper application and high concentrations can lead to systemic absorption of the anesthetic drugs, raising a critical question: why is numbing cream not recommended for unmonitored use?.

What is the highest percentage of benzocaine?

4 min read
Over-the-counter benzocaine products are widely available in various concentrations, with the highest percentage of benzocaine found in "maximum strength" topical applications often being 20%. While effective for temporary pain relief, using these higher concentrations requires careful attention to safety guidelines, especially regarding the rare but serious risk of methemoglobinemia.