Will Zosyn Cover MRSA? Understanding the Limitations of Piperacillin-Tazobactam
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3 min read
A widespread misconception exists that broad-spectrum antibiotics, like Zosyn, are effective against all serious bacterial infections, but this is untrue for resistant strains like MRSA. The critical answer to 'Will Zosyn cover MRSA?' is no, because methicillin-resistant *Staphylococcus aureus* (MRSA) has a specific resistance mechanism that renders Zosyn ineffective.