Tag: Methotrexate injection

In a study of patients with rheumatoid arthritis, mean and median pain scores for methotrexate injections were found to be low, but some patients still experience moderate to severe pain. For individuals receiving subcutaneous methotrexate injections, learning how to make a methotrexate injection less painful is a critical step towards consistent treatment and improved quality of life. This guide explores various strategies, from preparation and technique to managing anxiety, to help reduce injection discomfort.

According to the Arthritis Foundation, transitioning from oral to injectable methotrexate is a common strategy when patients experience persistent gastrointestinal (GI) issues. The central question for many is, however, is methotrexate injection easier on the stomach in practice, and why does this happen?